Explore Early-Life Microbiome Development with Advanced Metagenomics
Leverage Cosmos-Hub for comprehensive infant microbiome analysis to inform clinical studies, nutritional product development, and early-life interventions.
Why Infant Microbiome Research Matters
The infant microbiome critically shapes early-life health, immunity, and long-term developmental outcomes. From breastfeeding and infant formula to delivery methods and environmental exposures, understanding microbial composition and function during infancy provides essential insights for clinical interventions, nutritional formulations, and personalized pediatric care. Cosmos-Hub enables researchers to deeply explore infant microbiomes, empowering impactful research in digestive health, metabolic and immune system development, allergy prevention, and nutritional supplementation.
Cosmos-Hub’s state-of-the-art microbiome profiling tools, including our CHAMP Human profiler, support comprehensive exploration of the infant gut microbiome. Key research areas include:
Evaluating how different nutritional formulations and supplements (e.g., human milk oligosaccharides) modulate gut microbiome composition, bringing infant microbiota closer to breastfed profiles and supporting gut maturation
Investigating microbiota changes in response to extensively hydrolyzed formulas or amino acid-based formulas in infants with cow's milk protein allergy (CMPA), influencing both microbiome and metabolome
Understanding how microbiome modulation through human milk oligosaccharides (HMOs) reduces respiratory infections and promotes healthy gut development
Stool samples provide critical insight into the gut microbiome of infants in the first 1000 days of life. Cosmos-Hub has been used for many research studies and for the purpose of developing new infant health products
Cosmos-Hub has been used to help identify the role of the microbiome in infant skin conditions such Atopic Dermatitis, diaper rash and rare diseases as well as part of understanding of the impact of the NICU on infant health and development.
Understand the impact of HMO's on the infant microbiome as well track species and strains from mother to baby using CHAMP
How Cosmos-Hub Helps
Shotgun Metagenomics and CHAMP Profiling
Our shotgun metagenomics services provide high-resolution insights into the human microbiome. Using our proprietary CHAMP profiler—the most sensitive and accurate human microbiome profiler available—we offer detailed taxonomic and functional profiling to help researchers explore how microbial communities influence human health.
Functional Profiling
Our functional profiling for stool samples leverages curated gut-metabolic modules to explore microbial contributions to key processes, including:
Short-chain fatty acid (SCFA) production for gut health.
CAZyme analysis for fiber degradation and dietary metabolism.
Bile acid metabolism for gut-liver interactions.
KEGG module integration, offering a comprehensive overview of metabolic pathways affecting digestion and metabolic health.
MetaCyc Database: A comprehensive metabolic pathway database that provides insights into microbial enzymatic functions and biochemical reactions.
Enzyme Commission (EC) Classification: Organizes enzymes based on their catalytic activity, aiding in the identification of microbial enzymatic roles.
Gene Ontology (GO): A framework for categorizing microbial genes based on their associated biological processes, molecular functions, and cellular components.
Pfam Database: A collection of protein families and domains that helps characterize microbial proteins and their functional roles in metabolism and gene expression.
