Antimicrobial Resistance (AMR) Monitoring
Strain-Level AMR Detection with Unmatched Precision and Speed
Profile resistance genes and track emerging threats across clinical, environmental, and food microbiomes — no coding required, just upload and analyze with Cosmos-Hub.
Why Antimicrobial Resistance Profiling Matters
Antimicrobial resistance (AMR) is a growing global health crisis, responsible for millions of deaths annually. Surveillance and early detection are critical for limiting outbreaks, guiding treatment, and informing stewardship programs. Conventional culture-based AMR screening is slow, incomplete, and limited to known pathogens.
Cosmos-Hub enables ultra-fast, strain-level AMR gene profiling directly from sequencing data—empowering researchers, clinicians, and regulators to act swiftly with high-confidence results.
Example Sample Types for AMR Surveillance
- Clinical isolates and polymicrobial samples
- Environmental swabs (hospital, wastewater, agriculture)
- Human or animal microbiome samples
- Food products and processing environments
- Longitudinal studies of antibiotic exposure or treatment
- Cohort comparisons for AMR gene carriage and diversity
How Cosmos-Hub Powers AMR Research and Surveillance
Identifies AMR genes using k-mer-based, strain-resolved detection methods
Differentiates shared (homologous) vs. unique resistance biomarkers
Calculates coverage and abundance through composite k-mer stats
Profiles resistance across bacterial species in a host-agnostic framework
Relevant Pipelines
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Kepler™: Host-Agnostic Resistome & Virulome Profiling
Powered by the Kepler™ infrastructure, this pipeline uses curated k-mer biomarkers from ResFinder and VFDB to detect antimicrobial resistance (AMR) genes and virulence factors (VFs) directly from raw reads without genome assembly. Its biomarker-based scoring and hierarchical classification enable accurate quantification across classes and genes.
This pipeline is ideal for AMR surveillance, diagnostic microbiology, and functional microbial profiling.
Ready to Track Resistance with Confidence?
Frequently Asked Questions
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What AMR databases does Cosmos-Hub use?
The platform integrates curated nucleotide sequences from ResFinder and classifies them into shared and unique biomarker attributes for maximum resolution.
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Does it support detection in mixed samples?
Yes. Cosmos-Hub can detect resistance genes even in complex, polymicrobial datasets without host or species bias.
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Can I quantify resistance gene abundance?
Absolutely. Abundance is estimated using weighted k-mer and coverage depth metrics to reflect gene prevalence.
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How fast is the AMR analysis pipeline?
Most samples yield complete AMR/VF profiles within 1–3 hours. -
Is this platform suitable for environmental and food testing?
Yes. Cosmos-Hub is designed for multi-domain use, including clinical, environmental, and agricultural AMR surveillance.