Infant Microbiome Analysis Platform
Explore Early-Life Microbiome Development with Advanced Metagenomics
Discover the potential of Cosmos-Hub for comprehensive infant microbiome analysis, designed to propel clinical studies, nutritional product development, and early-life interventions.
How Cosmos-Hub Supports Infant Microbiome Research
Cosmos-Hub is tailored to advance data analytics into the infant microbiome, offering research teams the ability to conduct high-resolution profiling and comparisons of microbial communities with unmatched precision and speed.
Research teams benefit from sensitive and accurate taxonomic profiling, functional characterization, and metabolic pathway exploration specifically tailored to infant stool, skin, and breast milk samples. Cosmos-Hub’s streamlined reporting and customizable analytics ensure rapid turnaround and actionable insights, supporting clinical trials, nutritional formulation studies, and foundational science in immune and metabolic development.
Key Features:
- No-Code Platform: Cloud-based software requiring no specialized bioinformatics knowledge
- Integrated Workflow: End-to-end profiling, statistics, storage, and AI interpretation
- RITA AI Co-Pilot: AI-powered data interpretation with scientific referencing
- Atlas Database: Access to 40,000+ samples for comparative meta-analysis
- Enterprise Security: AWS-based solution with secure team sharing and MFA
- Multi-Omics Support: Handles 16S, shotgun metagenomics, ITS, and metabolomics analysis
Shotgun Metagenomics and CHAMP Profiling
Cutting-edge infant microbiome analysis is transforming our understanding of how the infant gut microbiome develops and influences health and disease throughout the first year of life. By using shotgun metagenomics approaches and the precise CHAMP profiler, researchers can track microbial composition, relative abundance, and beneficial bacteria such as Bifidobacterium Breve in the infant gut.
These tools reveal the impact of variables like mode of delivery, breast milk/formula feeding, and antibiotic exposure on microbial colonization, shaping the gut-brain axis, immune system development, and the overall implications for infant health and neurocognitive outcomes, as shown in studies by supported by Cmbio . Note links below…
Our shotgun metagenomics services provide high-resolution insights into the human microbiome. Using our proprietary CHAMP profiler—the most sensitive and accurate human microbiome profiler available—we offer detailed taxonomic and functional profiling to help researchers explore how microbial communities influence human health.
Functional Profiling
Delving into functional profiling of the infant gut microbiome is essential for understanding how microbial contributions support immune system maturation, gut health, and the development of the central nervous system during infancy.
This approach reveals how gut microbes and infant gut bacteria, equipped to produce short-chain fatty acids and metabolize human milk oligosaccharides, interact with dietary and environmental exposures—such as preterm birth, maternal stress, and antibiotic exposure—to influence health outcomes and disease risk in human infants. Insights from the infant intestinal microbiota and adult gut microbiota highlight the importance of microbial functional diversity in the gastrointestinal tract, contributing to healthy gut microbiome ecology and immune responses.
Why Infant Microbiome Research Matters
The infant microbiome critically shapes early-life health, immunity, and long-term developmental outcomes. From breastfeeding and infant formula to delivery methods and environmental exposures, understanding microbial composition and function during infancy provides essential insights for clinical interventions, nutritional formulations, and personalized pediatric care.
Cosmos-Hub enables researchers to deeply explore infant microbiomes, empowering impactful research in digestive health, metabolic and immune system development, allergy prevention, and nutritional supplementation.
Applications in Infant Microbiome Research
Cosmos-Hub’s state-of-the-art microbiome profiling tools, including our CHAMP Human profiler, support comprehensive exploration of the infant gut microbiome. Key research areas include:
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Infant formula studies
Evaluating how different nutritional formulations and supplements (e.g., human milk oligosaccharides) modulate gut microbiome composition, bringing infant microbiota closer to breastfed profiles and supporting gut maturation
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Clinical trials
Investigating microbiota changes in response to extensively hydrolyzed formulas or amino acid-based formulas in infants with cow's milk protein allergy (CMPA), influencing both microbiome and metabolome
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Immune and metabolic development
Understanding how microbiome modulation through human milk oligosaccharides (HMOs) reduces respiratory infections and promotes healthy gut development
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Delivery mode studies
Comparing microbial diversity and functional
Popular Sample Types
|
Sample Type |
Core Insights Provided |
Key Features & Applications |
|
Stool |
Gut microbial composition, SCFA production, impact of delivery mode, formula/breastfeeding, allergy risk, immune/metabolic development |
Taxonomic/functional profiling, clinical trial support, metabolic pathway analysis |
|
Skin |
Microbiome shifts with emollient use, atopic dermatitis risk, impact of NICU environment |
Skin health tracking, rare disease monitoring, environmental microbiome exposure studies |
|
Breast Milk |
HMO-driven microbial modulation, transmission of beneficial bacteria, maternal-infant strain tracking |
Mother-to-infant microbial transfer mapping, nutritional formulation research, HMO studies |
Publications and Success Stories
Real-World Impact of Human Microbiome Analysis with Cosmos-Hub
Cosmos-Hub has been instrumental in numerous studies exploring human microbiomes. Here are some key publications highlighting its impact:
- Shifts in Infant Skin Microbiome at 2 Months after Short-Term Emollient Use from Birth Are Associated with Reduced Prevalence of Atopic Dermatitis at 12 Months in a High-Risk Cohort. Stamatas GN, Insel R, Sørensen N, Palleja A, Moll JM, Oddos T, Chaoimh CN, O'B Hourihane J, Irvine AD. J Invest Dermatol. 2025. https://doi.org/10.1016/j.jid.2025.03.017
- Safety, efficacy, and impact on gut microbial ecology of a Bifidobacterium longum subspecies infantis LMG11588 supplementation in healthy term infants: a randomized, double-blind, controlled trial in the Philippines. Capeding MRZ, Phee LCM, Ming C, Noti M, Vidal K, Le Carrou G, Frézal A, Moll JM, Vogt JK, Myers PN, Nielsen BH, Boulangé CL, Samuel TM, Berger B, Cercamondi CI. Front Nutr. 2023. https://doi.org/10.3389/fnut.2023.1319873
- Infant Formula With a Specific Blend of Five Human Milk Oligosaccharides Drives the Gut Microbiota Development and Improves Gut Maturation Markers: A Randomized Controlled Trial. Bosheva M, Tokodi I, Krasnow A, Pedersen HK, Lukjancenko O, Eklund AC, Grathwohl D, Sprenger N, Berger B, Cercamondi CI; 5 HMO Study Investigator Consortium. Front Nutr. 2022. https://doi.org/10.3389/fnut.2022.920362
- Multi-omics analysis reveals the influence of genetic and environmental risk factors on developing gut microbiota in infants at risk of celiac disease. Leonard MM, Karathia H, Pujolassos M, Troisi J, Valitutti F, Subramanian P, Camhi S, Kenyon V, Colucci A, Serena G, Cucchiara S, Montuori M, Malamisura B, Francavilla R, Elli L, Fanelli B, Colwell R, Hasan N, Zomorrodi AR, Fasano A; CD-GEMM Team. Microbiome. 2020. https://doi.org/10.1186/s40168-020-00906-w
- Comparison of Infant Gut and Skin Microbiota, Resistome and Virulome Between Neonatal Intensive Care Unit (NICU) Environments. Hourigan SK, Subramanian P, Hasan NA, Ta A, Klein E, Chettout N, Huddleston K, Deopujari V, Levy S, Baveja R, Clemency NC, Baker RL, Niederhuber JE, Colwell RR. Front Microbiol. 2018. https://doi.org/10.3389/fmicb.2018.01361
Start Your Human Microbiome Research Today
Unlock the power of high-resolution microbiome analysis with Cosmos-Hub.
